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Novel Adenovirus type 5 vaccine platform induces cellular immunity against HIV-1 Gag, Pol, Nef despite the presence of Ad5 immunity

Recombinant Adenovirus serotype 5 (Ad5) vectors have been used as vaccine platforms in numerous animal and human clinical studies. The immune response induced by Ad5 vaccines can be mitigated due to pre-existing Ad5 immunity. We report here the use of a novel Ad5 platform to induce cellular immune r...

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Bibliografische gegevens
Hoofdauteurs: Gabitzsch, Elizabeth S., Xu, Younong, Yoshida, Lois H., Balint, Joseph, Amalfitano, Andrea, Jones, Frank R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767427/
https://ncbi.nlm.nih.gov/pubmed/19559110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.06.028
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