Predictors of HVTN 503 MRK-AD5 HIV-1 gag/pol/nef Vaccine Induced Immune Responses

BACKGROUND: Phambili, the Merck (MRK)-Adenovirus Type 5 (Ad5) HIV-1 gag/pol/nef subtype B vaccine study, conducted in South Africa, suspended enrollment and vaccination when companion study, Step, was found non-efficacious. Although the vaccine did not prevent HIV-1 infection or lower viral-load set...

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Bibliographic Details
Main Authors: Hopkins, Kathryn L., Laher, Fatima, Otwombe, Kennedy, Churchyard, Gavin, Bekker, Linda-Gail, DeRosa, Stephen, Nchabeleng, Maphoshane, Mlisana, Koleka, Kublin, James, Gray, Glenda
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121165/
https://ncbi.nlm.nih.gov/pubmed/25090110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103446
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