Overexpression of vascular endothelial growth factor C increases growth and alters the metastatic pattern of orthotopic PC-3 prostate tumors

BACKGROUND: Prostate cancer metastasizes to regional lymph nodes and distant sites but the roles of lymphatic and hematogenous pathways in metastasis are not fully understood. METHODS: We studied the roles of VEGF-C and VEGFR3 in prostate cancer metastasis by blocking VEGFR3 using intravenous adenov...

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Autors principals: Tuomela, Johanna, Valta, Maija, Seppänen, Jani, Tarkkonen, Kati, Väänänen, H Kalervo, Härkönen, Pirkko
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767356/
https://ncbi.nlm.nih.gov/pubmed/19821979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-362
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