Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion

Lung cancer is characterized by abnormal cell growth and invasion, and the actin cytoskeleton plays a major role in these processes. The focal adhesion protein paxillin is a target of a number of oncogenes involved in key signal transduction and important in cell motility and migration. In lung canc...

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Hauptverfasser: Jagadeeswaran, Ramasamy, Surawska, Hanna, Krishnaswamy, Soundararajan, Janamanchi, Varalakshmi, Mackinnon, A. Craig, Seiwert, Tanguy Y., Loganathan, Sivakumar, Kanteti, Rajani, Reichman, Trevor, Nallasura, Vidya, Schwartz, Stuart, Faoro, Leonardo, Wang, Yi-Ching, Girard, Luc, Tretiakova, Maria S., Ahmed, Salman, Zumba, Osvaldo, Soulii, Lioubov, Bindokas, Vytas P., Szeto, Livia L., Gordon, Gavin J., Bueno, Raphael, Sugarbaker, David, Lingen, Mark W., Sattler, Martin, Krausz, Thomas, Vigneswaran, Wickii, Natarajan, Viswanathan, Minna, John, Vokes, Everett E., Ferguson, Mark K., Husain, Aliya N., Salgia, Ravi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767335/
https://ncbi.nlm.nih.gov/pubmed/18172305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-1998
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