Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion

Lung cancer is characterized by abnormal cell growth and invasion, and the actin cytoskeleton plays a major role in these processes. The focal adhesion protein paxillin is a target of a number of oncogenes involved in key signal transduction and important in cell motility and migration. In lung canc...

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Autori principali: Jagadeeswaran, Ramasamy, Surawska, Hanna, Krishnaswamy, Soundararajan, Janamanchi, Varalakshmi, Mackinnon, A. Craig, Seiwert, Tanguy Y., Loganathan, Sivakumar, Kanteti, Rajani, Reichman, Trevor, Nallasura, Vidya, Schwartz, Stuart, Faoro, Leonardo, Wang, Yi-Ching, Girard, Luc, Tretiakova, Maria S., Ahmed, Salman, Zumba, Osvaldo, Soulii, Lioubov, Bindokas, Vytas P., Szeto, Livia L., Gordon, Gavin J., Bueno, Raphael, Sugarbaker, David, Lingen, Mark W., Sattler, Martin, Krausz, Thomas, Vigneswaran, Wickii, Natarajan, Viswanathan, Minna, John, Vokes, Everett E., Ferguson, Mark K., Husain, Aliya N., Salgia, Ravi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767335/
https://ncbi.nlm.nih.gov/pubmed/18172305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-1998
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