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C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes

Cancers typically harbour several mutant forms of key cellular genes that contribute to its complex phenotype. Our lab has previously identified gain-of-function mutations in some of the receptor tyrosine kinases such as c-Met in lung cancer. In order to investigate the mutant gene in the context of...

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Detalhes bibliográficos
Main Authors: Siddiqui, Shahid S., Loganathan, Sivakumar, Krishnaswamy, Soundararajan, Faoro, Leonardo, Jagadeeswaran, Ramasamy, Salgia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580824/
https://ncbi.nlm.nih.gov/pubmed/18340114
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