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Mechanism for the Pyridoxal Neutralization of Isoniazid Action on Mycobacterium tuberculosis

In Sauton's synthetic liquid medium, 10 μg of pyridoxal per ml completely protected Mycobacterium tuberculosis (H37R(a)) from the effects of a minimal inhibitory concentration of isoniazid (0.01 μg/ml). (14)C-labeled isoniazid was employed to study the nature of this protective effect. Uptake of the...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Beggs, William H., Jenne, John W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1967
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276733/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4963783/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.94.4.793-797.1967
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