Mechanism for the Pyridoxal Neutralization of Isoniazid Action on Mycobacterium tuberculosis

In Sauton's synthetic liquid medium, 10 μg of pyridoxal per ml completely protected Mycobacterium tuberculosis (H37R(a)) from the effects of a minimal inhibitory concentration of isoniazid (0.01 μg/ml). (14)C-labeled isoniazid was employed to study the nature of this protective effect. Uptake of the...

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Bibliografische Detailangaben

Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Beggs, William H., Jenne, John W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1967
Schlagworte:	Infection and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4963783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.94.4.793-797.1967
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