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Mechanism for the Pyridoxal Neutralization of Isoniazid Action on Mycobacterium tuberculosis

In Sauton's synthetic liquid medium, 10 μg of pyridoxal per ml completely protected Mycobacterium tuberculosis (H37R(a)) from the effects of a minimal inhibitory concentration of isoniazid (0.01 μg/ml). (14)C-labeled isoniazid was employed to study the nature of this protective effect. Uptake o...

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Detalhes bibliográficos
Main Authors: Beggs, William H., Jenne, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 1967
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC276733/
https://ncbi.nlm.nih.gov/pubmed/4963783
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