β(2) Integrin deficiency yields unconventional double-negative T cells distinct from mature classical natural killer T cells in mice

Expressed on leucocytes, β(2) integrins (CD11/CD18) are specifically involved in leucocyte function. Using a CD18-deficient (CD18(−/−)) mouse model, we here report on their physiological role in lymphocyte differentiation and trafficking. CD18(−/−) mice present with a defect in the distribution of l...

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Detalhes bibliográficos
Main Authors: Oreshkova, Tsvetelina, Wang, Honglin, Seier, Anne M, Sindrilaru, Anca, Varga, Georg, Grabbe, Stephan, Scharffetter-Kochanek, Karin, Peters, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767317/
https://ncbi.nlm.nih.gov/pubmed/19740384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03116.x
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