Chaperone-Targeting Cytotoxin and Endoplasmic Reticulum Stress-Inducing Drug Synergize to Kill Cancer Cells

Diverse physiological and therapeutic insults that increase the amount of unfolded or misfolded proteins in the endoplasmic reticulum (ER) induce the unfolded protein response, an evolutionarily conserved protective mechanism that manages ER stress. Glucose-regulated protein 78/immunoglobulin heavy-...

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Detalhes bibliográficos
Main Authors: Backer, Joseph M, Krivoshein, Arcadius V, Hamby, Carl V, Pizzonia, John, Gilbert, Kenneth S, Ray, Yonaton S, Brand, Harrison, Paton, Adrienne W, Paton, James C, Backer, Marina V
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767218/
https://ncbi.nlm.nih.gov/pubmed/19881952
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