Chaperone-Targeting Cytotoxin and Endoplasmic Reticulum Stress-Inducing Drug Synergize to Kill Cancer Cells

Diverse physiological and therapeutic insults that increase the amount of unfolded or misfolded proteins in the endoplasmic reticulum (ER) induce the unfolded protein response, an evolutionarily conserved protective mechanism that manages ER stress. Glucose-regulated protein 78/immunoglobulin heavy-...

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Autores principales: Backer, Joseph M, Krivoshein, Arcadius V, Hamby, Carl V, Pizzonia, John, Gilbert, Kenneth S, Ray, Yonaton S, Brand, Harrison, Paton, Adrienne W, Paton, James C, Backer, Marina V
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767218/
https://ncbi.nlm.nih.gov/pubmed/19881952
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