Dietary cholesterol worsens adipose tissue macrophage accumulation and atherosclerosis in obese LDL receptor-deficient mice

OBJECTIVE: Chronic systemic inflammation accompanies obesity and predicts development of cardiovascular disease. Dietary cholesterol has been shown to increase inflammation and atherosclerosis in LDL receptor-deficient (LDLR-/-) mice. This study was undertaken to determine whether dietary cholestero...

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Autori principali: Subramanian, Savitha, Han, Chang Yeop, Chiba, Tsuyoshi, McMillen, Timothy S., Wang, Shari A., Haw, Antonio, Kirk, Elizabeth A., O’Brien, Kevin D., Chait, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767166/
https://ncbi.nlm.nih.gov/pubmed/18239153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.107.157685
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