Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, can progress to steatohepatitis (NASH) and advanced liver disease. Mechanisms that underlie this progression remain poorly understood, partly due to lack of good animal models that resemble human NASH. We...

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Détails bibliographiques
Auteurs principaux: Subramanian, Savitha, Goodspeed, Leela, Wang, Shari, Kim, Jinkyu, Zeng, Lixia, Ioannou, George N., Haigh, W. Geoffrey, Yeh, Matthew M., Kowdley, Kris V., O'Brien, Kevin D., Pennathur, Subramaniam, Chait, Alan
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2011
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151683/
https://ncbi.nlm.nih.gov/pubmed/21690266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M016246
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