Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, can progress to steatohepatitis (NASH) and advanced liver disease. Mechanisms that underlie this progression remain poorly understood, partly due to lack of good animal models that resemble human NASH. We...

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Detalhes bibliográficos
Main Authors: Subramanian, Savitha, Goodspeed, Leela, Wang, Shari, Kim, Jinkyu, Zeng, Lixia, Ioannou, George N., Haigh, W. Geoffrey, Yeh, Matthew M., Kowdley, Kris V., O'Brien, Kevin D., Pennathur, Subramaniam, Chait, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151683/
https://ncbi.nlm.nih.gov/pubmed/21690266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M016246
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