Deficiency of Invariant Natural Killer T Cells Does Not Protect Against Obesity but Exacerbates Atherosclerosis in Ldlr(−/−) Mice

Obesity is a chronic inflammatory state characterized by altered levels of adipose tissue immune cell populations. Natural killer T (NKT) cells are CD1d restricted lymphocyte subsets that recognize lipid antigens whose level decreases in obese adipose tissue. However, studies in mice with deficiency...

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Pubblicato in:Int J Mol Sci
Autori principali: Subramanian, Savitha, Goodspeed, Leela, Wang, Shari, Ding, Yilei, O’Brien, Kevin D., Getz, Godfrey S., Chait, Alan, Reardon, Catherine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855732/
https://ncbi.nlm.nih.gov/pubmed/29419749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020510
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