Tesaglitazar, a dual peroxisome proliferator-activated receptor alpha/gamma agonist, reduces atherosclerosis in female low density lipoprotein receptor deficient mice

OBJECTIVE: The transcription factors, peroxisome proliferator-activated receptors (PPAR) alpha (α) and gamma (γ), which are involved in lipid and glucose homeostasis, also exert modulatory actions on vascular cells where they exhibit anti-inflammatory and anti-proliferative properties. Hence PPAR ag...

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Bibliographic Details
Main Authors: Chira, Ebele C., McMillen, Timothy S., Wang, Shari, Haw, Antonio, O’Brien, Kevin D., Wight, Thomas N., Chait, Alan
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702263/
https://ncbi.nlm.nih.gov/pubmed/17214992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2006.12.012
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