B cells and aging: molecules and mechanisms

Recent advances allow aging-associated changes in B-cell function to be approached at a mechanistic level. Reduced expression of genes crucial to lineage commitment and differentiation yield diminished B-cell production. Moreover, intrinsic differences in the repertoire generated by B-cell precursor...

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Bibliografiske detaljer
Main Authors: Cancro, Michael P., Hao, Yi, Scholz, Jean L., Riley, Richard L., Frasca, Daniela, Dunn-Walters, Deborah K., Blomberg, Bonnie B.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766868/
https://ncbi.nlm.nih.gov/pubmed/19540810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2009.04.005
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