Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential

Hematopoietic stem cell (HSC) engraftment is a multistep process involving HSC homing to bone marrow, self-renewal, proliferation, and differentiation to mature blood cells. Here, we show that loss of p190-B RhoGTPase activating protein, a negative regulator of Rho GTPases, results in enhanced long-...

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Bibliographic Details
Main Authors: Xu, Haiming, Eleswarapu, Satyam, Geiger, Hartmut, Szczur, Kathleen, Daria, Deidre, Zheng, Yi, Settleman, Jeffrey, Srour, Edward F., Williams, David A., Filippi, Marie-Dominique
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2009
Subjects:
Hematopoiesis and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766675/
https://ncbi.nlm.nih.gov/pubmed/19713466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-205815
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