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The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signaling

Neutrophil migration to sites of infection is the first line of cellular defense. A key event of migration is the maintenance of a polarized morphology, which is characterized by a single leading edge of filamentous actin and a contractile uropod devoid of filamentous actin protrusions. Using a mous...

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Bibliografski detalji
Glavni autori: Szczur, Kathleen, Zheng, Yi, Filippi, Marie-Dominique
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403354/
https://ncbi.nlm.nih.gov/pubmed/19752396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-195164
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