Intracellular ‘boosting’ of darunavir using known transport inhibitors in primary PBMC

AIMS: ABCB1, some ABCCs and SLCOs have been reported to affect the intracellular accumulation of various protease inhibitors in vitro and ex vivo. Darunavir is the most recently licensed protease inhibitor and we sought to investigate the ability of transport inhibitors to influence its intracellula...

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Bibliografiske detaljer
Main Authors: Kwan, Wai San, Janneh, Omar, Hartkoorn, Ruben, Chandler, Becky, Khoo, Saye, Back, David, Owen, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2009
Fag:
Drug Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766476/
https://ncbi.nlm.nih.gov/pubmed/19740394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03462.x
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