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Interactions of Tenofovir, Lamivudine, Abacavir and Didanosine in Primary Human Cells

Certain triple nucleoside/tide reverse transcriptase inhibitor (NRTI) regimens containing tenofovir (TDF) have been associated with rapid early treatment failure. The mechanism is unknown, but may be at the level of drug transport. We measured the lipophilicity of the drugs [(3)H]-lamivudine (3TC),...

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Detalhes bibliográficos
Main Authors: Janneh, Omar, Khoo, Saye H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864238/
https://ncbi.nlm.nih.gov/pubmed/24310499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics3020326
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