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Maraviroc modelling strategy: use of early phase 1 data to support a semi-mechanistic population pharmacokinetic model
AIMS: To model the basic pharmacokinetic (PK) characteristics of maraviroc to construct an integrated semi-mechanistic PK model for use in later population PK analyses. METHODS: Three analyses were performed utilizing intravenous, oral and radiolabel data. Firstly, a PK disposition model was develop...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766474/ https://ncbi.nlm.nih.gov/pubmed/19740392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03455.x |
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