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A population pharmacokinetic meta-analysis of maraviroc in healthy volunteers and asymptomatic HIV-infected subjects

AIMS: To develop a population pharmacokinetic model for maraviroc, a noncompetitive CCR5 antagonist, after oral administration of tablets to healthy volunteers and asymptomatic HIV-infected subjects and to quantify the inherent variability and influence of covariates on the parameters of the model....

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Autori principali: Chan, Phylinda L S, Weatherley, Barry, McFadyen, Lynn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311413/
https://ncbi.nlm.nih.gov/pubmed/18333869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03139.x
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