Mapping Quantitative Traits in Unselected Families: Algorithms and Examples

Linkage analysis has been widely used to identify from family data genetic variants influencing quantitative traits. Common approaches have both strengths and limitations. Likelihood ratio tests typically computed in variance component analysis can accommodate large families but are highly sensitive...

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Main Authors: Dupuis, Josée, Shi, Jianxin, Manning, Alisa K., Benjamin, Emelia J., Meigs, James B., Cupples, L. Adrienne, Siegmund, David
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766029/
https://ncbi.nlm.nih.gov/pubmed/19278016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20413
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