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Mapping Quantitative Traits in Unselected Families: Algorithms and Examples
Linkage analysis has been widely used to identify from family data genetic variants influencing quantitative traits. Common approaches have both strengths and limitations. Likelihood ratio tests typically computed in variance component analysis can accommodate large families but are highly sensitive...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766029/ https://ncbi.nlm.nih.gov/pubmed/19278016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20413 |
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