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The Level of Macrophage uPA Expression is an Important Determinant of Atherosclerotic Lesion Growth in Apoe(−/−) Mice
OBJECTIVE: Enhanced plasminogen activation, mediated by overexpression of urokinase-type plasminogen activator (uPA), accelerates atherosclerosis in apolipoprotein E-null mice. However, the mechanisms through which uPA acts remain unclear. In addition, although elevated uPA expression can accelerate...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766014/ https://ncbi.nlm.nih.gov/pubmed/19729604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.195529 |
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