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Refinement of lentiviral vector for improved RNA processing and reduced rates of self inactivation repair

BACKGROUND: Lentiviral gene therapy vectors are now finding clinical application. In order to fully exploit their potential it is important that vectors are made as efficient and as safe as possible. Accordingly, we have modified a previously reported vector to improve RNA processing, minimise Human...

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Detalles Bibliográficos
Main Authors: Koldej, Rachel M, Anson, Donald S
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765960/
https://ncbi.nlm.nih.gov/pubmed/19811661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-86
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