New structural insights and molecular-modelling studies of 4-methyl-5-β-hydroxyethylthiazole kinase from Pyrococcus horikoshii OT3 (PhThiK)

4-Methyl-5-β-hydroxyethylthiazole kinase (ThiK) catalyses the phosphorylation of the hydroxyl group of 4-methyl-5-β-hydroxyethylthiazole. This work reports the first crystal structure of an archaeal ThiK: that from Pyrococcus horikoshii OT3 (PhThiK) at 1.85 Å resolution with a phosphate ion occupyin...

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מידע ביבליוגרפי
Main Authors: Jeyakanthan, Jeyaraman, Thamotharan, Subbiah, Velmurugan, Devadasan, Rao, Vaijayanthimala Surya Narayna, Nagarajan, Shanthi, Shinkai, Akeo, Kuramitsu, Seiki, Yokoyama, Shigeyuki
פורמט: Artigo
שפה:Inglês
יצא לאור: International Union of Crystallography 2009
נושאים:
Structural Communications
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765881/
https://ncbi.nlm.nih.gov/pubmed/19851002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109036033
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