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ATF3 plays a protective role against toxicity by N-terminal fragment of mutant huntingtin in stable PC12 cell line

Huntington's disease is a progressive neurodegenerative disorder caused by a polyglutamine expansion near the N-terminus of huntingtin. The mechanisms of polyglutamine neurotoxicity, and cellular responses are not fully understood. We have studied gene expression profiles by cDNA array using an...

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Detalhes bibliográficos
Main Authors: Liang, Yideng, Jiang, Haibing, Ratovitski, Tamara, Jie, Chunfa, Nakamura, Masayuki, Hirschhorn, Ricky R., Wang, Xiaofang, Smith, Wanli W., Hai, Tsonwin, Poirier, Michelle A., Ross, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765721/
https://ncbi.nlm.nih.gov/pubmed/19559011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.06.049
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