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Mapping the Active Site in a Chemzyme: Diversity in the N-Substituent in the Catalytic Asymmetric Aziridination of Imines

[Image: see text] The active site of the aziridination catalyst derived from either the VANOL or VAPOL ligand is larger than expected and can accommodate not only significant substitution on the diarylmethyl unit of the imine but also that alkyl (but not perfluorylalkyl) substituents on the aryl gro...

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Detalhes bibliográficos
Main Authors: Zhang, Yu, Lu, Zhenjie, Desai, Aman, Wulff, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765527/
https://ncbi.nlm.nih.gov/pubmed/18989967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802431v
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