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Insights into the reactivation of cobalamin-dependent methionine synthase

Cobalamin-dependent methionine synthase (MetH) is a modular protein that catalyzes the transfer of a methyl group from methyltetrahydrofolate to homocysteine to produce methionine and tetrahydrofolate. The cobalamin cofactor, which serves as both acceptor and donor of the methyl group, is oxidized o...

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Bibliographic Details
Main Authors: Koutmos, Markos, Datta, Supratim, Pattridge, Katherine A., Smith, Janet L., Matthews, Rowena G.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765455/
https://ncbi.nlm.nih.gov/pubmed/19846791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906132106
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