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Metal active site elasticity linked to activation of homocysteine in methionine synthases

Enzymes possessing catalytic zinc centers perform a variety of fundamental processes in nature, including methyl transfer to thiols. Cobalamin-independent (MetE) and cobalamin-dependent (MetH) methionine synthases are two such enzyme families. Although they perform the same net reaction, transfer of...

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Détails bibliographiques
Auteurs principaux: Koutmos, Markos, Pejchal, Robert, Bomer, Theresa M., Matthews, Rowena G., Smith, Janet L., Ludwig, Martha L.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265165/
https://ncbi.nlm.nih.gov/pubmed/18296644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709960105
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