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Factors modulating conformational equilibria in large modular proteins: A case study with cobalamin-dependent methionine synthase

In the course of catalysis or signaling, large multimodular proteins often undergo conformational changes that reposition the modules with respect to one another. The mechanisms that direct the reorganization of modules in these proteins are of considerable importance, but distinguishing alternate c...

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Autors principals: Bandarian, Vahe, Ludwig, Martha L., Matthews, Rowena G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC166199/
https://ncbi.nlm.nih.gov/pubmed/12832615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1133218100
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