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Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells

BACKGROUND: Ionizing radiation (IR) therapy is a primary treatment for glioblastoma multiforme (GBM), a common and devastating brain tumor in humans. IR has been shown to induce PI3K-Akt activation in many cell types, and activation of the PI3K-Akt signaling pathway has been correlated with radiores...

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Detalhes bibliográficos
Main Authors: Li, Hui-Fang, Kim, Jung-Sik, Waldman, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765447/
https://ncbi.nlm.nih.gov/pubmed/19828040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-4-43
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