Hepatitis B virus inhibition in mice by lentiviral vector mediated short hairpin RNA

BACKGROUND: Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma. The major challenges for current therapies are the low efficacy of current drugs and the occurrence of drug resistant HBV mutations. RNA interference (RNAi) of virus-specific genes...

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Hauptverfasser: Deng, Lei, Li, Guoqiang, Xi, Lisen, Yin, Aihong, Gao, Yun, You, Wei, Wang, Xuehao, Sun, Beicheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765442/
https://ncbi.nlm.nih.gov/pubmed/19804649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-9-73
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