Hepatitis B virus inhibition in mice by lentiviral vector mediated short hairpin RNA

BACKGROUND: Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma. The major challenges for current therapies are the low efficacy of current drugs and the occurrence of drug resistant HBV mutations. RNA interference (RNAi) of virus-specific genes...

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Detalhes bibliográficos
Main Authors: Deng, Lei, Li, Guoqiang, Xi, Lisen, Yin, Aihong, Gao, Yun, You, Wei, Wang, Xuehao, Sun, Beicheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765442/
https://ncbi.nlm.nih.gov/pubmed/19804649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-9-73
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