Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models

BACKGROUND: Tumour stromal myofibroblasts can promote tumour invasion. As these cells are genetically more stable than cancer cells, there has been enormous interest in developing targeted molecular therapies against them. Chloride intracellular channel 4 (CLIC4) and reactive oxygen species (ROS) ha...

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Bibliographische Detailangaben
Hauptverfasser: Yao, Qin, Qu, Xun, Yang, Qifeng, Good, David A, Dai, Shuzhen, Kong, Beihua, Wei, Ming Q
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765417/
https://ncbi.nlm.nih.gov/pubmed/19781102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-78
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