Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models

BACKGROUND: Tumour stromal myofibroblasts can promote tumour invasion. As these cells are genetically more stable than cancer cells, there has been enormous interest in developing targeted molecular therapies against them. Chloride intracellular channel 4 (CLIC4) and reactive oxygen species (ROS) ha...

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Detalhes bibliográficos
Main Authors: Yao, Qin, Qu, Xun, Yang, Qifeng, Good, David A, Dai, Shuzhen, Kong, Beihua, Wei, Ming Q
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765417/
https://ncbi.nlm.nih.gov/pubmed/19781102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-78
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