Bioavailability of diazepam after intramuscular injection of its water-soluble prodrug alone or with atropine–pralidoxime in healthy volunteers

BACKGROUND AND PURPOSE: The aim of this study was to assess the relative bioavailability of diazepam after administration of diazepam itself or as a water-soluble prodrug, avizafone, in humans. EXPERIMENTAL APPROACH: The study was conducted in an open, randomized, single-dose, three-way, cross-over...

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Autores principales: Abbara, C, Rousseau, JM, Turcant, A, Lallement, G, Comets, E, Bardot, I, Clair, P, Diquet, B
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2009
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765321/
https://ncbi.nlm.nih.gov/pubmed/19681868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00330.x
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