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Profiling the T-cell receptor beta-chain repertoire by massively parallel sequencing
T-cell receptor (TCR) genomic loci undergo somatic V(D)J recombination, plus the addition/subtraction of nontemplated bases at recombination junctions, in order to generate the repertoire of structurally diverse T cells necessary for antigen recognition. TCR beta subunits can be unambiguously identi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765271/ https://ncbi.nlm.nih.gov/pubmed/19541912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.092924.109 |
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