Loading...

Cystic Fibrosis Transmembrane Conductance Regulator: Using Differential Reactivity toward Channel-Permeant and Channel-Impermeant Thiol-Reactive Probes To Test a Molecular Model for the Pore

[Image: see text] The sixth transmembrane segment (TM6) of the CFTR chloride channel has been intensively investigated. The effects of amino acid substitutions and chemical modification of engineered cysteines (cysteine scanning) on channel properties strongly suggest that TM6 is a key component of...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Alexander, Christopher, Ivetac, Anthony, Liu, Xuehong, Norimatsu, Yohei, Serrano, Jose R., Landstrom, Allison, Sansom, Mark, Dawson, David C.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2009
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765204/
https://ncbi.nlm.nih.gov/pubmed/19754156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901314c
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!