Development and Validation of A Semi-Automated Assay for the Highly Sensitive Quantification of Biolimus A9 in Human Whole Blood Using High Performance Liquid Chromatography-Tandem Mass Spectrometry

Drug-eluting stents are sustained-release intra-coronary devices that are usually coated with a few hundred micrograms of drug. Measuring the drugs that are released over weeks in order to assess human pharmacokinetics is a challenge that requires assays with high sensitivity. We developed and valid...

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Hlavní autoři: Clavijo, Claudia, Strom, Tobin, Moll, Vanessa, Betts, Ronald, Zhang, Yan Ling, Christians, Uwe, Bendrick-Peart, Jamie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765116/
https://ncbi.nlm.nih.gov/pubmed/19762292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2009.08.020
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