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Differential utilization of T cell receptor TCRα/TCRδ locus variable region gene segments is mediated by accessibility

T cell receptor (TCR) variable region exons are assembled from germline V, (D), and J gene segments, each of which is flanked by recombination signal (RS) sequences that are composed of a conserved heptamer, a spacer of 12 or 23 bp, and a characteristic nonamer. V(D)J recombination only occurs betwe...

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Bibliografski detalji
Glavni autori: Lee, Yu Nee, Alt, Frederick W., Reyes, Julia, Gleason, Megan, Zarrin, Ali A., Jung, David
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765100/
https://ncbi.nlm.nih.gov/pubmed/19805067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909723106
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