Intact Long-Term Potentiation but Reduced Connectivity between Neocortical Layer 5 Pyramidal Neurons in a Mouse Model of Rett Syndrome

Mutations in MECP2 cause Rett syndrome and some related forms of mental retardation and autism. Mecp2-null mice exhibit symptoms reminiscent of Rett syndrome including deficits in learning. Previous reports demonstrated impaired long-term potentiation (LTP) in slices of symptomatic Mecp2-null mice,...

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Hlavní autoři: Dani, Vardhan S., Nelson, Sacha B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765053/
https://ncbi.nlm.nih.gov/pubmed/19741133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1019-09.2009
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