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Intact Long-Term Potentiation but Reduced Connectivity between Neocortical Layer 5 Pyramidal Neurons in a Mouse Model of Rett Syndrome
Mutations in MECP2 cause Rett syndrome and some related forms of mental retardation and autism. Mecp2-null mice exhibit symptoms reminiscent of Rett syndrome including deficits in learning. Previous reports demonstrated impaired long-term potentiation (LTP) in slices of symptomatic Mecp2-null mice,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765053/ https://ncbi.nlm.nih.gov/pubmed/19741133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1019-09.2009 |
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