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DNA polymerase β and PARP activities in base excision repair in living cells

To examine base excision repair (BER) capacity in the context of living cells, we developed and applied a plasmid-based reporter assay. Non-replicating plasmids containing unique DNA base lesions were designed to express luciferase only after lesion repair had occurred, and luciferase expression in...

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Bibliografski detalji
Glavni autori: Masaoka, Aya, Horton, Julie K., Beard, William A., Wilson, Samuel H.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765039/
https://ncbi.nlm.nih.gov/pubmed/19748837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.08.004
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