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Biochemical mechanisms in drug-induced liver injury: Certainties and doubts

Drug-induced liver injury is a significant and still unresolved clinical problem. Limitations to knowledge about the mechanisms of toxicity render incomplete the detection of hepatotoxic potential during preclinical development. Several xenobiotics are lipophilic substances and their transformation...

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מידע ביבליוגרפי
Main Authors: Grattagliano, Ignazio, Bonfrate, Leonilde, Diogo, Catia V, Wang, Helen H, Wang, David QH, Portincasa, Piero
פורמט: Artigo
שפה:Inglês
יצא לאור: The WJG Press and Baishideng 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764962/
https://ncbi.nlm.nih.gov/pubmed/19842215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.4865
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