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Biochemical mechanisms in drug-induced liver injury: Certainties and doubts
Drug-induced liver injury is a significant and still unresolved clinical problem. Limitations to knowledge about the mechanisms of toxicity render incomplete the detection of hepatotoxic potential during preclinical development. Several xenobiotics are lipophilic substances and their transformation...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The WJG Press and Baishideng
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764962/ https://ncbi.nlm.nih.gov/pubmed/19842215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.4865 |
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