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AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply
AMP-activated protein kinase (AMPK) senses changes in the intracellular AMP/ATP ratio, switching off energy-consuming processes and switching on catabolic pathways in response to energy depletion. Here, we show that AMPK down-regulates rRNA synthesis under glucose restriction by phosphorylating the...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764937/ https://ncbi.nlm.nih.gov/pubmed/19815529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909873106 |
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