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AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply

AMP-activated protein kinase (AMPK) senses changes in the intracellular AMP/ATP ratio, switching off energy-consuming processes and switching on catabolic pathways in response to energy depletion. Here, we show that AMPK down-regulates rRNA synthesis under glucose restriction by phosphorylating the...

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Detaylı Bibliyografya
Asıl Yazarlar: Hoppe, Sven, Bierhoff, Holger, Cado, Ivana, Weber, Andrea, Tiebe, Marcel, Grummt, Ingrid, Voit, Renate
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764937/
https://ncbi.nlm.nih.gov/pubmed/19815529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909873106
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